Detection of preoperative wilms tumor rupture with CT: a report from the Children's Oncology Group.

ABSTRACT:

Purpose

To retrospectively determine the diagnostic performance of computed tomography (CT) in identifying the presence or absence of preoperative Wilms tumor rupture.

Materials and methods

The cohort was derived from the AREN03B2 study of the Children's Oncology Group. The study was approved by the institutional review board and was compliant with HIPAA. Written informed consent was obtained before enrollment. The diagnosis of Wilms tumor rupture was established by central review of notes from surgery and/or pathologic examination. Seventy Wilms tumor cases with rupture were matched to 70 Wilms tumor controls without rupture according to age and tumor weight (within 6 months and 50 g, respectively). CT scans were independently reviewed by two radiologists, and the following

SUBMITTER: Khanna G 

PROVIDER: S-EPMC3558872 | biostudies-literature | 2013 Feb

REPOSITORIES: biostudies-literature