Coronary aspirate TNFα reflects saphenous vein bypass graft restenosis risk in diabetic patients.

ABSTRACT:

Background

Patients with diabetes mellitus (DM) have an increased risk for periprocedural complications and adverse cardiac events after percutaneous coronary intervention. We addressed the potential for coronary microvascular obstruction and restenosis in patients with and without DM undergoing stenting for saphenous vein bypass graft (SVG) stenosis under protection with a distal occlusion/aspiration device.

Methods

SVG plaque volume and composition were analyzed using intravascular ultrasound before stent implantation. Percent diameter stenosis was determined from quantitative coronary angiography before, immediately after and 6 months after stent implantation. Coronary aspirate was retrieved during stent implantation and divided into particulate debris and plasma. Total c

SUBMITTER: Baars T 

PROVIDER: S-EPMC3560373 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature