Activity in inferior parietal and medial prefrontal cortex signals the accumulation of evidence in a probability learning task.

ABSTRACT: In an uncertain environment, probabilities are key to predicting future events and making adaptive choices. However, little is known about how humans learn such probabilities and where and how they are encoded in the brain, especially when they concern more than two outcomes. During functional magnetic resonance imaging (fMRI), young adults learned the probabilities of uncertain stimuli through repetitive sampling. Stimuli represented payoffs and participants had to predict their occurrence to maximize their earnings. Choices indicated loss and risk aversion but unbiased estimation of probabilities. BOLD response in medial prefrontal cortex and angular gyri increased linearly with the probability of the currently observed stimulus, untainted by its value. Connectivity analyses during rest

SUBMITTER: d'Acremont M 

PROVIDER: S-EPMC3561043 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature