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Suboptimal health: a new health dimension for translational medicine.


ABSTRACT:

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Background

One critical premise of disease-related biomarkers is the definition of the counterpart normality. Contrary to pre-clinical models that can be carefully tailored according to scientific need, heterogeneity and uncontrollability is the essence of humans in health studies. Fully characterization of consistent parameters that define the normal population is the basis to individual differences normalization irrelevant to a given disease process. Self claimed normal status may not represent health because asymptomatic subjects may carry chronic diseases or diseases at their early stage such as cancer, diabetes and hypertension.

Methods

This paper exemplifies the characterization of the suboptimal health status (SHS) which represents a new public heal

SUBMITTER: Wang W 

PROVIDER: S-EPMC3561061 | biostudies-literature | 2012 Nov

REPOSITORIES: biostudies-literature