Brain structure abnormalities in adolescent girls with conduct disorder.

ABSTRACT:

Background

Conduct disorder (CD) in female adolescents is associated with a range of negative outcomes, including teenage pregnancy and antisocial personality disorder. Although recent studies have documented changes in brain structure and function in male adolescents with CD, there have been no neuroimaging studies of female adolescents with CD. Our primary objective was to investigate whether female adolescents with CD show changes in grey matter volume. Our secondary aim was to assess for sex differences in the relationship between CD and brain structure.

Methods

Female adolescents with CD (n = 22) and healthy control participants matched in age, performance IQ and handedness (n = 20) underwent structural magnetic resonance imaging. Group comparisons of grey matter volume

SUBMITTER: Fairchild G 

PROVIDER: S-EPMC3562487 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature