Using model-based functional MRI to locate working memory updates and declarative memory retrievals in the fronto-parietal network.

ABSTRACT: In this study, we used model-based functional MRI (fMRI) to locate two functions of the fronto-parietal network: declarative memory retrievals and updating of working memory. Because regions in the fronto-parietal network are by definition coherently active, locating functions within this network is difficult. To overcome this problem, we applied model-based fMRI, an analysis method that uses predictions of a computational model to inform the analysis. We applied model-based fMRI to five previously published datasets with associated computational cognitive models, and subsequently integrated the results in a meta-analysis. The meta-analysis showed that declarative memory retrievals correlated with activity in the inferior frontal gyrus and the anterior cingulate, whereas updating of workin

SUBMITTER: Borst JP 

PROVIDER: S-EPMC3562808 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature