Changes in Timing and kinematics of goal directed eye-hand movements in early-stage Parkinson's disease.

ABSTRACT:

Unlabelled

Objective

Many daily activities involve intrinsic or extrinsic goal-directed eye and hand movements. An extensive visuomotor coordination network including nigro-striatal pathways is required for efficient timing and positioning of eyes and hands. The aim of this study was to investigate how Parkinson's disease (PD) affects eye-hand coordination in tasks with different cognitive complexity.

Methods

We used a touch screen, an eye-tracking device and a motion capturing system to quantify changes in eye-hand coordination in early-stage PD patients (H&Y < 2.5) and age-matched controls. Timing and kinematics of eye and hand were quantified in four eye-hand coordination tasks (pro-tapping, dual planning, anti-tapping and spatial memory task).

Results

In t

SUBMITTER: Muilwijk D 

PROVIDER: S-EPMC3563471 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature