A new spatane diterpenoid from the cultured soft coral Sinularia leptoclados.

ABSTRACT: A new spatane diterpenoid, leptoclalin A (1), along with two previously reported known norcembranoid diterpenes (2 and 3), were isolated from a cultured soft coral Sinularia leptoclados. The structures were determined by extensive spectroscopic analyses and by comparison with the spectral data of related known compounds. Metabolite 1 is rarely found in spatane skeletons reported from soft corals. In addition, compound 1 exhibited weak cytotoxicity towards human tumor cell lines T-47 D and K-562.

SUBMITTER: Tsai TC 

PROVIDER: S-EPMC3564161 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature