A structured interview guide for global impressions: increasing reliability and scoring accuracy for CNS trials.

ABSTRACT:

Unlabelled

Background

The clinical global impression of severity (CGI-S) scale is a frequently used rating instrument for the assessment of global severity of illness in Central Nervous System (CNS) trials. Although scoring guidelines have been proposed to anchor these scores, the collection of sufficient documentation to support the derived score is not part of any standardized interview procedure. It is self evident that the absence of a standardized, documentary format can affect inter-rater reliability and may adversely affect the accuracy of the resulting data.

Method

We developed a structured interview guide for global impressions (SIGGI) and evaluated the instrument in a 2-visit study of ambulatory patients with Major Depressive Disorder (MDD) or schizophrenia

SUBMITTER: Targum SD 

PROVIDER: S-EPMC3564924 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature