Effect of congenital heart defects on language development in toddlers with Down syndrome.

ABSTRACT:

Background

Down syndrome (DS, OMIM #190685) is the most commonly identified genetic form of intellectual disability with congenital heart defect (CHD) occurring in 50% of cases. With advances in surgical techniques and an increasing lifespan, this has necessitated a greater understanding of the neurodevelopmental consequences of CHDs. Herein, we explore the impact of CHD on language development in children with DS.

Methods

Twenty-nine children with DS were observed systematically in parent-child interactions using the Communication Play Protocol to evaluate their language use; they also completed the Mullen Scales of Early Learning and MacArthur Communication Development Inventory. Mean ages were 31.2 months for children with DS and CHD (DS + CHD, n = 12) and 32.1 months for

SUBMITTER: Visootsak J 

PROVIDER: S-EPMC3565078 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature