A trial of intracranial-pressure monitoring in traumatic brain injury.

ABSTRACT:

Background

Intracranial-pressure monitoring is considered the standard of care for severe traumatic brain injury and is used frequently, but the efficacy of treatment based on monitoring in improving the outcome has not been rigorously assessed.

Methods

We conducted a multicenter, controlled trial in which 324 patients 13 years of age or older who had severe traumatic brain injury and were being treated in intensive care units (ICUs) in Bolivia or Ecuador were randomly assigned to one of two specific protocols: guidelines-based management in which a protocol for monitoring intraparenchymal intracranial pressure was used (pressure-monitoring group) or a protocol in which treatment was based on imaging and clinical examination (imaging-clinical examination group). The primary

SUBMITTER: Chesnut RM 

PROVIDER: S-EPMC3565432 | biostudies-literature | 2012 Dec

REPOSITORIES: biostudies-literature