Working alliance and its relationship to outcomes in a randomized controlled trial (RCT) of antipsychotic medication.

ABSTRACT:

Background

Long acting injections (LAI) have been associated with perceptions of coercion in cross sectional studies but there have been no longitudinal studies of the effects on clinical relationships with newer depot medications.

Method

Randomized controlled trial with (50) participants with a diagnosis of schizophrenia randomized to risperidone LAI or oral atypical antipsychotic medication. The main outcome was the Working Alliance Inventory (WAI) with background variables (symptoms, side effect, social functioning, quality of life) measured before randomization and at two years.

Results

At follow-up (14 risperidone LAI and 16 oral medication) analyses including predictors of missing data and baseline score showed a trend for those on risperidone LAI to reduce WAI

SUBMITTER: Wykes T 

PROVIDER: S-EPMC3565872 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature