Alternaric acid: formal synthesis and related studies.

ABSTRACT: A silyl glyoxylate three-component-coupling methodology has been exploited to achieve a formal synthesis, an analogue to an intermediate in a distinct formal synthetic route, and a third (unique) approach to the natural product alternaric acid. Highlighted in this study is the versatility of silyl glyoxylates to engage a variety of nucleophile and electrophile pairs to provide wide latitude in the approach to complex molecule synthesis.

SUBMITTER: Slade MC 

PROVIDER: S-EPMC3566800 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature