Genome-wide analysis of protein disorder in Arabidopsis thaliana: implications for plant environmental adaptation.

ABSTRACT: Intrinsically disordered proteins/regions (IDPs/IDRs) are currently recognized as a widespread phenomenon having key cellular functions. Still, many aspects of the function of these proteins need to be unveiled. IDPs conformational flexibility allows them to recognize and interact with multiple partners, and confers them larger interaction surfaces that may increase interaction speed. For this reason, molecular interactions mediated by IDPs/IDRs are particularly abundant in certain types of protein interactions, such as those of signaling and cell cycle control. We present the first large-scale study of IDPs in Arabidopsis thaliana, the most widely used model organism in plant biology, in order to get insight into the biological roles of these proteins in plants. The work includes a compar

SUBMITTER: Pietrosemoli N 

PROVIDER: S-EPMC3567104 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature