Ontology highlight
ABSTRACT:
SUBMITTER: Weel-Sneve R
PROVIDER: S-EPMC3567139 | biostudies-literature | 2013
REPOSITORIES: biostudies-literature
PLoS genetics 20130207 2
The functions of several SOS regulated genes in Escherichia coli are still unknown, including dinQ. In this work we characterize dinQ and two small RNAs, agrA and agrB, with antisense complementarity to dinQ. Northern analysis revealed five dinQ transcripts, but only one transcript (+44) is actively translated. The +44 dinQ transcript translates into a toxic single transmembrane peptide localized in the inner membrane. AgrB regulates dinQ RNA by RNA interference to counteract DinQ toxicity. Thus ...[more]