A comparison of buprenorphine taper outcomes between prescription opioid and heroin users.

ABSTRACT:

Objectives

Dependence on prescription opioids (PO) is a growing problem. Although most research with buprenorphine has focused on heroin-dependent populations, we hypothesize that individuals dependent on PO display characteristics that may predict different outcomes in treatment, particularly in short-term taper procedures in which comorbidities such as pain conditions may complicate taper.

Methods

This secondary data analysis examined differences in outcomes between PO users (n = 90) and heroin users (n = 426) after a buprenorphine taper. Data were collected in a multisite randomized clinical trial conducted by the National Drug Abuse Treatment Clinical Trials Network at 11 study sites across the United States. After a 4-week buprenorphine induction/stabilization phase, 51

SUBMITTER: Nielsen S 

PROVIDER: S-EPMC3567310 | biostudies-literature | 2013 Jan-Feb

REPOSITORIES: biostudies-literature