Genomic background and generation time influence deleterious mutation rates in Daphnia.

ABSTRACT: Understanding how genetic variation is generated and how selection shapes mutation rates over evolutionary time requires knowledge of the factors influencing mutation and its effects on quantitative traits. We explore the impact of two factors, genomic background and generation time, on deleterious mutation in Daphnia pulicaria, a cyclically parthenogenic aquatic microcrustacean, using parallel mutation-accumulation experiments. The deleterious mutational properties of life-history characters for individuals from two different populations, and for individuals maintained at two different generation times, were quantified and compared. Mutational properties varied between populations, especially for clutch size, suggesting that genomic background influences mutational properties for some cha

SUBMITTER: Latta LC 

PROVIDER: S-EPMC3567742 | biostudies-literature | 2013 Feb

REPOSITORIES: biostudies-literature