A simple and effective strategy for labeling cysteine sulfenic acid in proteins by utilization of β-ketoesters as cleavable probes.

ABSTRACT: β-ketoesters are robust probes for labeling sulfenic acid (-SOH) proteins allowing quantitative cleavage of the tag for improved analysis of the labeled peptides by MS.

SUBMITTER: Qian J 

PROVIDER: S-EPMC3568515 | biostudies-literature | 2012 Apr

REPOSITORIES: biostudies-literature