Hepatitis C virus isolates from Argentina disclose a novel genotype 1-associated restriction pattern.

ABSTRACT: Hepatitis C virus isolates which disclosed a novel genotype 1-associated restriction pattern by restriction fragment length polymorphism analysis were characterized. Except for a mother and child pair, the patients were unrelated. Sequence analysis showed a G-->A substitution leading to a new RsaI recognition site. Phylogenetic analysis revealed that these isolates constitute a novel genetic lineage within the main cluster of genotype 1 strains.

SUBMITTER: Gismondi MI 

PROVIDER: S-EPMC356882 | biostudies-literature | 2004 Mar

REPOSITORIES: biostudies-literature