Morphological macrovascular alterations in complex regional pain syndrome type I demonstrated by increased intima-media thickness.

ABSTRACT:

Background

Although intima-media thickness (IMT) was increased in several inflammatory diseases, studies investigating whether the inflammatory processes lead to macrovascular alteration with increased IMT in complex regional pain syndrome (CRPS) lack.

Methods

Using ultrasound (high-resolution B-mode), we compared bilaterally the IMT of the common carotid artery (CCA-IMT), the radial artery (RA-IMT), the brachial artery (BRA-IMT) and the quotient QRA/CCA, in CRPS type I (n=17), peripheral nerve injury (PNI, n=17) and pain-free controls (PFC, n=22, matched to CRPS by gender, age and traditional cardiovascular risk factors).

Statistics

Spearman's correlation, paired t-test, ANOVA (p<0.05).

Results

Compared to PFC, RA-IMT were significantly increased in both patie

SUBMITTER: Derenthal N 

PROVIDER: S-EPMC3570292 | biostudies-literature | 2013 Feb

REPOSITORIES: biostudies-literature