Higher peritoneal protein clearance as a risk factor for cardiovascular disease in peritoneal dialysis patient.

ABSTRACT:

Background and aims

Although a number of studies have been published on peritoneal protein clearance (PrCl) and its association with patient outcomes, the results have been inconsistent. Therefore, the intent of this study was to evaluate the impact of PrCl on cardiovascular disease (CVD) and mortality in peritoneal dialysis (PD) patients.

Methods

This prospective observational study included a total of 540 incident patients who started PD at NHIC Ilsan Hospital, Korea from January 2000 to December 2009. Two different types of analyses such as intention-to-treat and as-treated were used.

Results

Correlation analyses revealed that PrCl was positively correlated with diabetes, pulse pressure, C-reactive protein (CRP) level, dialysate/plasma creatinine ratio (D/P cr) at

SUBMITTER: Chang TI 

PROVIDER: S-EPMC3571965 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature