Estimating ancestry and heterozygosity of hybrids using molecular markers.

ABSTRACT:

Background

Hybridization, genetic mixture of distinct populations, gives rise to myriad recombinant genotypes. Characterizing the genomic composition of hybrids is critical for studies of hybrid zone dynamics, inheritance of traits, and consequences of hybridization for evolution and conservation. Hybrid genomes are often summarized either by an estimate of the proportion of alleles coming from each ancestral population or classification into discrete categories like F1, F2, backcross, or merely "hybrid" vs. "pure". In most cases, it is not realistic to classify individuals into the restricted set of classes produced in the first two generations of admixture. However, the continuous ancestry index misses an important dimension of the genotype. Joint consideration of ancestry togeth

SUBMITTER: Fitzpatrick BM 

PROVIDER: S-EPMC3572440 | biostudies-literature | 2012 Jul

REPOSITORIES: biostudies-literature