Molecular characterization of Chittoor (Batai) virus isolates from India.

ABSTRACT:

Background & objectives

Chittoor virus (CHITV) belongs to genus Orthobunyavirus, family Bunyaviridae. It has been isolated from various species of mosquitoes and pig from different parts of India. Five isolates of CHITV were characterized at the molecular level and compared with other Batai viruses (BATV) to find out any kind of reassortment in their genome.

Methods

Complete nucelocapsid (S), glycoprotein (M) and partial RNA polymerase (L) segments of CHITV were amplified and sequenced. These sequences were compared with those of Batai viruses, isolated from different geographical locations in Asia, Africa and Europe.

Results

Phylogenetic analysis revealed CHITV as a variant of BATV. High level of conservation was seen among the CHITV isolates studied. The CHITV seque

SUBMITTER: Yadav PD 

PROVIDER: S-EPMC3573600 | biostudies-literature | 2012 Nov

REPOSITORIES: biostudies-literature