Phylogenetic analysis of Torque Teno Virus genome from Pakistani isolate and incidence of co-infection among HBV/HCV infected patients.

ABSTRACT:

Background

Torque Teno Virus (TTV) was the first single stranded circular DNA virus to be discovered that infects humans. Although there have been numerous reports regarding the prevalence of TTV from other countries of South Asia, there is severe lack of information regarding its prevalence in Pakistan. Thus the present study compiles the first indigenous report to comprehensively illustrate the incidence of the virus in uninfected and hepatitis infected population from Pakistan. Another aim of the study was to present the sequence of full length TTV genome from a local isolate and compare it with the already reported genome sequences from other parts of the world.

Methods

TTV DNA was screened in the serum of 116, 100 and 40 HBV infected, HCV infected and uninfected individ

SUBMITTER: Hussain T 

PROVIDER: S-EPMC3573928 | biostudies-literature | 2012 Dec

REPOSITORIES: biostudies-literature