Molecular epidemiology and complete genome characterization of H1N1pdm virus from India.

ABSTRACT:

Background

Influenza A virus is one of world's major uncontrolled pathogen, causing seasonal epidemic as well as global pandemic. This was evidenced by recent emergence and continued prevalent 2009 swine origin pandemic H1N1 Influenza A virus, provoking first true pandemic in the past 40 years. In the course of its evolution, the virus acquired many mutations and multiple unidentified molecular determinants are likely responsible for the ability of the 2009 H1N1 virus to cause increased disease severity in humans. Availability of limited data on complete genome hampers the continuous monitoring of this type of events. Outbreaks with considerable morbidity and mortality have been reported from all parts of the country.

Methods/results

Considering a large number of clinical ca

SUBMITTER: Sharma S 

PROVIDER: S-EPMC3574146 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature