Ontology highlight
ABSTRACT:
SUBMITTER: Kuhns S
PROVIDER: S-EPMC3575539 | biostudies-literature | 2013 Feb
REPOSITORIES: biostudies-literature
The Journal of cell biology 20130211 4
Despite the critical contributions of cilia to embryonic development and human health, key regulators of cilia formation await identification. In this paper, a functional RNA interference-based screen linked 30 novel protein kinases with ciliogenesis. Of them, we have studied the role of the microtubule (MT)-associated protein/MT affinity regulating kinase 4 (MARK4) in depth. MARK4 associated with the basal body and ciliary axoneme in human and murine cell lines. Ultrastructural and functional a ...[more]