Genetic predictors of cue- and stress-induced cigarette craving: an exploratory study.

ABSTRACT:

Unlabelled

Cigarette cravings in response to environmental cues and stressors are widely recognized as important predictors of smoking cessation outcomes. Accumulating evidence suggests that genetics plays a role in these craving responses, as well as in smoking cessation more generally. Previous studies of genetic polymorphisms have been limited by examination of single candidate genes and the use of broadly defined phenotypes (e.g., smoking history). In addition, research examining the similarities and differences between cue- and stress-induced cravings has been limited, although some evidence has suggested that they may have common genetic underpinnings. In the current study, we examined associations between a panel of 1,350 candidate genetic polymorphisms and craving responses

SUBMITTER: Erblich J 

PROVIDER: S-EPMC3576834 | biostudies-literature | 2012 Feb

REPOSITORIES: biostudies-literature