High serum uric acid and increased risk of type 2 diabetes: a systemic review and meta-analysis of prospective cohort studies.

ABSTRACT:

Objective

Current evidence suggests high serum uric acid may increase the risk of type 2 diabetes, but the association is still uncertain. The aim of the study was to evaluate the association between serum uric acid and future risk of type 2 diabetes by conducting a meta-analysis of prospective cohort studies.

Design and methods

We conducted a systematic literature search of the PubMed database through April 2012. Prospective cohort studies were included in meta-analysis that reported the multivariate adjusted relative risks (RRs) and the corresponding 95% confidence intervals (CIs) for the association between serum uric acid and risk of type 2 diabetes. We used both fix-effects and random-effects models to calculate the overall effect estimate. The heterogeneity across stud

SUBMITTER: Lv Q 

PROVIDER: S-EPMC3577701 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature