A randomized controlled trial of intensive periodontal therapy on metabolic and inflammatory markers in patients With ESRD: results of an exploratory study.

ABSTRACT:

Background

Periodontitis is a novel risk factor for inflammation and cardiovascular disease in the dialysis population. Limited information exists about the impact of periodontal therapy in patients receiving dialysis.

Study design

Randomized controlled trial to assess feasibility and gather preliminary data.

Setting & participants

Dialysis patients with moderate/severe chronic periodontitis.

Intervention

Intensive treatment, consisting of scaling and root planing, extraction of hopeless teeth, and placement of local-delivery antibiotics, was performed at the baseline visit for treatment-group patients and after study completion for control-group patients.

Outcomes

Outcomes were feasibility (screening, recruitment, enrollment, adverse events, and study w

SUBMITTER: Wehmeyer MM 

PROVIDER: S-EPMC3578050 | biostudies-literature | 2013 Mar

REPOSITORIES: biostudies-literature