Exposure to traffic emissions: associations with biomarkers of antioxidant status and oxidative damage.

ABSTRACT:

Background

Oxidative stress has been implicated as a possible mechanism for adverse health effects associated with traffic emissions. We examined the association of an estimate of traffic emissions with blood biomarkers of antioxidant capacity (glutathione, glutathione peroxidase, trolox-equivalent antioxidant capacity) and oxidative damage (thiobarbituric acid-reactive substances (TBARS)) among 1810 healthy women, randomly selected from Erie and Niagara Counties in Western New York.

Methods

A geographic traffic emission and meteorological dispersion model was used to estimate annual polycyclic aromatic hydrocarbon (PAH) exposure from traffic emissions for each woman based on her residence at the time of study. Associations of traffic-related PAH exposure with measures of ox

SUBMITTER: Li Y 

PROVIDER: S-EPMC3578064 | biostudies-literature | 2013 Feb

REPOSITORIES: biostudies-literature