Selective sweep in the Flotillin-2 region of European Drosophila melanogaster.

ABSTRACT: Localizing genes that are subject to recent positive selection is a major goal of evolutionary biology. In the model organism Drosophila melanogaster many attempts have been made in recent years to identify such genes by conducting so-called genome scans of selection. These analyses consisted in typing a large number of genetic markers along the genomes of a sample of individuals and then identifying those loci that harbor patterns of genetic variation, which are compatible with the ones generated by a selective sweep. In this study we conduct an in-depth analysis of a genomic region located on the X chromosome of D. melanogaster that was identified as a potential target of recent positive selection by a previous genome scan of selection. To this end we re-sequenced 20 kilobases around the

SUBMITTER: Werzner A 

PROVIDER: S-EPMC3578937 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature