Obesity in children with poorly controlled asthma: Sex differences.

ABSTRACT:

Background

Obesity increases asthma risk, and may alter asthma severity. In adults, sex appears to modify the effect of obesity on asthma. Among children, the effect of sex on the relationship between obesity and asthma severity remains less clear, particularly when considering race.

Objective

To determine how obesity affects disease characteristics in a diverse cohort of children with poorly controlled asthma, and if obesity effects are altered by sex.

Design

We analyzed 306 children between 6 and 17 years of age with poorly controlled asthma enrolled in a 6-month trial assessing lansoprazole for asthma control. In this secondary analysis, we determined associations between obesity and symptom severity, spirometry, exacerbation risk, airway biomarkers, bronchial reac

SUBMITTER: Lang JE 

PROVIDER: S-EPMC3578966 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature