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Glucose-neopentyl glycol (GNG) amphiphiles for membrane protein study.


ABSTRACT: The development of a new class of surfactants for membrane protein manipulation, "GNG amphiphiles", is reported. These amphiphiles display promising behavior for membrane proteins, as demonstrated recently by the high resolution structure of a sodium-pumping pyrophosphatase reported by Kellosalo et al. (Science, 2012, 337, 473).

SUBMITTER: Chae PS 

PROVIDER: S-EPMC3578972 | biostudies-literature | 2013 Mar

REPOSITORIES: biostudies-literature