Assessment of liver viscoelasticity by using shear waves induced by ultrasound radiation force.

ABSTRACT:

Purpose

To investigate the value of viscosity measured with ultrasonographic (US) elastography in liver fibrosis staging and to determine whether the use of a viscoelastic model to estimate liver elasticity can improve its accuracy in fibrosis staging.

Materials and methods

The study, which was performed from February 2010 to March 2011, was compliant with HIPAA and approved by the institutional review board. Written informed consent was obtained from each subject. Ten healthy volunteers (eight women and two men aged 27-55 years) and 35 patients with liver disease (17 women and 18 men aged 19-74 years) were studied by using US elasticity measurements of the liver (within 6 months of liver biopsy). US data were analyzed with the shear wave dispersion ultrasound vibrometry (SD

SUBMITTER: Chen S 

PROVIDER: S-EPMC3579173 | biostudies-literature | 2013 Mar

REPOSITORIES: biostudies-literature