Shifts in human skin and nares microbiota of healthy children and adults.

ABSTRACT:

Background

Characterization of the topographical and temporal diversity of the microbial collective (microbiome) hosted by healthy human skin established a reference for studying disease-causing microbiomes. Physiologic changes occur in the skin as humans mature from infancy to adulthood. Thus, characterizations of adult microbiomes might have limitations when considering pediatric disorders such as atopic dermatitis (AD) or issues such as sites of microbial carriage. The objective of this study was to determine if microbial communities at several body sites in children differed significantly from adults.

Methods

Using 16S-rRNA gene sequencing technology, we characterized and compared the bacterial communities of four body sites in relation to Tanner stage of human developme

SUBMITTER: Oh J 

PROVIDER: S-EPMC3580446 | biostudies-literature | 2012

REPOSITORIES: biostudies-literature