Early versus late parenteral nutrition in ICU patients: cost analysis of the EPaNIC trial.

ABSTRACT:

Introduction

The EPaNIC randomized controlled multicentre trial showed that postponing initiation of parenteral nutrition (PN) in ICU-patients to beyond the first week (Late-PN) enhanced recovery, as compared with Early-PN. This was mediated by fewer infections, accelerated recovery from organ failure and reduced duration of hospitalization. Now, the trial's preplanned cost analysis (N = 4640) from the Belgian healthcare payers' perspective is reported.

Methods

Cost data were retrieved from individual patient invoices. Undiscounted total healthcare costs were calculated for the index hospital stay. A cost tree based on acquisition of new infections and on prolonged length-of-stay was constructed. Contribution of 8 cost categories to total hospitalization costs was analyzed.

SUBMITTER: Vanderheyden S 

PROVIDER: S-EPMC3580642 | biostudies-literature | 2012 May

REPOSITORIES: biostudies-literature