Identification of uterine ion transporters for mineralisation precursors of the avian eggshell.

ABSTRACT:

Background

In Gallus gallus, eggshell formation takes place daily in the hen uterus and requires large amounts of the ionic precursors for calcium carbonate (CaCO3). Both elements (Ca2+, HCO3-) are supplied by the blood via trans-epithelial transport. Our aims were to identify genes coding for ion transporters that are upregulated in the uterine portion of the oviduct during eggshell calcification, compared to other tissues and other physiological states, and incorporate these proteins into a general model for mineral transfer across the tubular gland cells during eggshell formation.

Results

A total of 37 candidate ion transport genes were selected from our database of overexpressed uterine genes associated with eggshell calcification, and by analogy with mammalian transport

SUBMITTER: Jonchere V 

PROVIDER: S-EPMC3582589 | biostudies-literature | 2012 Sep

REPOSITORIES: biostudies-literature