Accurate decoding of sub-TR timing differences in stimulations of sub-voxel regions from multi-voxel response patterns.

ABSTRACT: We investigated the decoding of ocular dominance stimulations with millisecond-order timing difference from the blood oxygen level dependent (BOLD) signal in human functional magnetic resonance imaging (fMRI). In our experiment, ocular dominance columns were activated by monocular visual stimulation with 500- or 100- ms onset differences. We observed that the event-related hemodynamic response (HDR) in the human visual cortex was sensitive to the subtle onset difference. The HDR shapes were related to the stimulus timings in various manners: the timing difference was represented in either the amplitude of positive peak, amplitude of negative peak, delay of peak time, or response duration of HDR. These complex relationships were different across voxels and subjects. To find an informative f

SUBMITTER: Misaki M 

PROVIDER: S-EPMC3582847 | biostudies-literature | 2013 Feb

REPOSITORIES: biostudies-literature