Transcriptomic analysis of the stress response to weaning at housing in bovine leukocytes using RNA-seq technology.

ABSTRACT:

Background

Weaning of beef calves is a necessary husbandry practice and involves separating the calf from its mother, resulting in numerous stressful events including dietary change, social reorganisation and the cessation of the maternal-offspring bond and is often accompanied by housing. While much recent research has focused on the physiological response of the bovine immune system to stress in recent years, little is known about the molecular mechanisms modulating the immune response. Therefore, the objective of this study was to provide new insights into the molecular mechanisms underlying the physiological response to weaning at housing in beef calves using Illumina RNA-seq.

Results

The leukocyte transcriptome was significantly altered for at least 7 days following eit

SUBMITTER: O'Loughlin A 

PROVIDER: S-EPMC3583219 | biostudies-literature | 2012 Jun

REPOSITORIES: biostudies-literature