A RAD-based linkage map and comparative genomics in the gudgeons (genus Gnathopogon, Cyprinidae).

ABSTRACT:

Background

The construction of linkage maps is a first step in exploring the genetic basis for adaptive phenotypic divergence in closely related species by quantitative trait locus (QTL) analysis. Linkage maps are also useful for comparative genomics in non-model organisms. Advances in genomics technologies make it more feasible than ever to study the genetics of adaptation in natural populations. Restriction-site associated DNA (RAD) sequencing in next-generation sequencers facilitates the development of many genetic markers and genotyping. We aimed to construct a linkage map of the gudgeons of the genus Gnathopogon (Cyprinidae) for comparative genomics with the zebrafish Danio rerio (a member of the same family as gudgeons) and for the future QTL analysis of the genetic architect

SUBMITTER: Kakioka R 

PROVIDER: S-EPMC3583795 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature