International Cancer of the Pancreas Screening (CAPS) Consortium summit on the management of patients with increased risk for familial pancreatic cancer.

ABSTRACT:

Background

Screening individuals at increased risk for pancreatic cancer (PC) detects early, potentially curable, pancreatic neoplasia.

Objective

To develop consortium statements on screening, surveillance and management of high-risk individuals with an inherited predisposition to PC.

Methods

A 49-expert multidisciplinary international consortium met to discuss pancreatic screening and vote on statements. Consensus was considered reached if ≥ 75% agreed or disagreed.

Results

There was excellent agreement that, to be successful, a screening programme should detect and treat T1N0M0 margin-negative PC and high-grade dysplastic precursor lesions (pancreatic intraepithelial neoplasia and intraductal papillary mucinous neoplasm). It was agreed that the following were

SUBMITTER: Canto MI 

PROVIDER: S-EPMC3585492 | biostudies-literature | 2013 Mar

REPOSITORIES: biostudies-literature