Ontology highlight
ABSTRACT:
SUBMITTER: Garnett SA
PROVIDER: S-EPMC3586113 | biostudies-literature | 2013 Feb
REPOSITORIES: biostudies-literature
Garnett Sally Anne SA Martin Miguel M Jerusalem Guy G Petruzelka Lubos L Torres Roberto R Bondarenko Igor N IN Khasanov Rustem R Verhoeven Didier D Pedrini José L JL Smirnova Iva I Lichinitser Mikhail R MR Pendergrass Kelly K Lindemann Justin P O JP Di Leo Angelo A
Breast cancer research and treatment 20130203 1
Comparisons of duration of response (DoR) and duration of clinical benefit (DoCB) within clinical trials are prone to biases. To address these biases, we used new methodology to prospectively analyze expected DoR and expected DoCB. Objective response rate and clinical benefit rate were calculated for fulvestrant 500 and 250 mg, and used to calculate expected DoR and expected DoCB for each dose group. The ratios for expected DoR and expected DoCB (expected DoR500/expected DoR250 and expected DoCB ...[more]