Ontology highlight
ABSTRACT:
SUBMITTER:
PROVIDER: S-EPMC3586139 | biostudies-literature | 2010
REPOSITORIES: biostudies-literature
Drugs in R&D 20100101 4
Abiraterone acetate (CB 7630; CB7630; JNJ-212082), the 3β-acetate prodrug of abiraterone, is structurally related to ketoconazole and is being developed by Cougar Biotechnology as a hormonal therapy for advanced prostate and breast cancers. As a selective inhibitor of adrenal androgens, it is thought to be a safer product than existing second-line hormonal therapies. This review discusses the key development milestones and therapeutic trials of this drug. ...[more]