Safety of AS03-adjuvanted split-virion H1N1 (2009) pandemic influenza vaccine: a prospective cohort study.

ABSTRACT:

Objectives

To assess the safety of an AS03-adjuvanted split virion H1N1 (2009) vaccine (Pandemrix) in persons vaccinated during the national pandemic influenza vaccination campaign in the UK.

Design

Prospective, cohort, observational, postauthorisation safety study.

Setting

87 general practices forming part of the Medical Research Council General Practice Research Framework and widely distributed throughout England.

Participants

A cohort of 9143 individuals aged 7 months to 97 years who received at least one dose of the AS03-adjuvanted H1N1 pandemic vaccine during the national pandemic influenza vaccination campaign in the UK was enrolled. 94% completed the 6-month follow-up. Exclusion criteria were previous vaccination with other H1N1 pandemic vaccine and any

SUBMITTER: Nazareth I 

PROVIDER: S-EPMC3586178 | biostudies-literature | 2013

REPOSITORIES: biostudies-literature