Measuring and interpreting neuronal correlations.

ABSTRACT: Mounting evidence suggests that understanding how the brain encodes information and performs computations will require studying the correlations between neurons. The recent advent of recording techniques such as multielectrode arrays and two-photon imaging has made it easier to measure correlations, opening the door for detailed exploration of their properties and contributions to cortical processing. However, studies have reported discrepant findings, providing a confusing picture. Here we briefly review these studies and conduct simulations to explore the influence of several experimental and physiological factors on correlation measurements. Differences in response strength, the time window over which spikes are counted, spike sorting conventions and internal states can all markedly aff

SUBMITTER: Cohen MR 

PROVIDER: S-EPMC3586814 | biostudies-literature | 2011 Jun

REPOSITORIES: biostudies-literature