Primary treatments for clinically localised prostate cancer: a comprehensive lifetime cost-utility analysis.

ABSTRACT:

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WHAT'S KNOWN ON THE SUBJECT? AND WHAT DOES THE STUDY ADD?: Multiple treatment alternatives exist for localised prostate cancer, with few high-quality studies directly comparing their comparative effectiveness and costs. The present study is the most comprehensive cost-effectiveness analysis to date for localised prostate cancer, conducted with a lifetime horizon and accounting for survival, health-related quality-of-life, and cost impact of secondary treatments and other downstream events, as well as primary treatment choices. The analysis found minor differences, generally slightly favouring surgical methods, in quality-adjusted life years across treatment options. However, radiation therapy (RT) was consistently more expensive than surgery, and some alternatives, e.g.

SUBMITTER: Cooperberg MR 

PROVIDER: S-EPMC3587031 | biostudies-literature | 2013 Mar

REPOSITORIES: biostudies-literature