Determination of PDCD5 in Peripheral Blood Serum of Cancer Patients.

ABSTRACT:

Objective

Programmed cell death 5 (PDCD5) is an apoptosis related gene and plays an important role in the pathogenesis and development of cancer. Whether PDCD5 is present in peripheral blood serum has not been reported. The aim of this study is to determine the contents of PDCD5 protein in peripheral blood serum of cancer patients, as well as normal subjects.

Methods

ELISA was used to detect the serum PDCD5 concentrations in 100 normal persons, 83 patients with breast cancer, 74 patients with gastrointestinal tract cancer and 41 patients with lung cancer. The results were statistically analyzed and discussed.

Results

PDCD5 could be detected in peripheral blood serum in both normal subjects and cancer patients. The serum PDCD5 contents in normal persons ranged from 3.8

SUBMITTER: Wang Y 

PROVIDER: S-EPMC3587550 | biostudies-literature | 2011 Sep

REPOSITORIES: biostudies-literature