Low prevalence of neurocognitive impairment in early diagnosed and managed HIV-infected persons.

ABSTRACT:

Objective

To describe the prevalence of neurocognitive impairment (NCI) among early diagnosed and managed HIV-infected persons (HIV+) compared to HIV-negative controls.

Methods

We performed a cross-sectional study among 200 HIV+ and 50 matched HIV-uninfected (HIV-) military beneficiaries. HIV+ patients were categorized as earlier (<6 years of HIV, no AIDS-defining conditions, and CD4 nadir >200 cells/mm(3)) or later stage patients (n = 100 in each group); both groups were diagnosed early and had access to care. NCI was diagnosed using a comprehensive battery of standardized neuropsychological tests.

Results

HIV+ patients had a median age of 36 years, 91% were seroconverters (median window of 1.2 years), had a median duration of HIV of 5 years, had a CD4 nadir of 319,

SUBMITTER: Crum-Cianflone NF 

PROVIDER: S-EPMC3589242 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature