Modulation of large-scale brain networks by transcranial direct current stimulation evidenced by resting-state functional MRI.

ABSTRACT:

Background

Brain areas interact mutually to perform particular complex brain functions such as memory or language. Furthermore, under resting-state conditions several spatial patterns have been identified that resemble functional systems involved in cognitive functions. Among these, the default-mode network (DMN), which is consistently deactivated during task periods and is related to a variety of cognitive functions, has attracted most attention. In addition, in resting-state conditions some brain areas engaged in focused attention (such as the anticorrelated network, AN) show a strong negative correlation with DMN; as task demand increases, AN activity rises, and DMN activity falls.

Objective

We combined transcranial direct current stimulation (tDCS) with functional magnet

SUBMITTER: Pena-Gomez C 

PROVIDER: S-EPMC3589751 | biostudies-literature | 2012 Jul

REPOSITORIES: biostudies-literature