Frequency of and risk factors for poor cognitive performance in hemodialysis patients.

ABSTRACT:

Objective

There are few detailed data on cognition in patients undergoing dialysis. We evaluated the frequency of and risk factors for poor cognitive performance using detailed neurocognitive testing.

Methods

In this cross-sectional cohort study, 314 hemodialysis patients from 6 Boston-area hemodialysis units underwent detailed cognitive assessment. The neuropsychological battery assessed a broad range of functions, with established age-, sex-, and education-matched normative scores. Principal component analysis was used to derive composite scores for memory and executive function domains. Risk factors for each domain were evaluated using linear regression adjusting for age, sex, race, and education status. Analyses were repeated in those with Mini-Mental State Examination (

SUBMITTER: Sarnak MJ 

PROVIDER: S-EPMC3590049 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature